Research & Evidence Library

Evidence first. Claims second.

This library distinguishes authoritative evidence, peer-reviewed literature, RTH synthesis, patient-authored observations, research manuscripts, study-development materials, and open validation questions. The Neurocardiac Model™ is presented as evidence-informed and hypothesis-generating—not as a diagnostic or treatment standard.

Research architecture

One public index. Multiple evidence layers.

RestartingTheHeart.com serves as the RTH ecosystem gateway. NeurocardiacMethod.com is the designated specialist scientific property; until that dedicated professional site is fully deployed, this page serves as the public index for the research pipeline and appropriate collaboration pathways.

Neurocardiac science

Autonomic physiology, stress response, neurohormonal signaling, cardiac recovery, brain-heart interaction, and related translational literature.

Wearables & measurement

Validation research for HRV, heart rate, readiness, sleep, consumer sensors, device data, and longitudinal signal interpretation.

AI & evidence systems

Explainability, provenance, AI governance, interoperability, clinical decision-support boundaries, and responsible health-data use for SuperstarIQ.

Research maturity pathway

A research question is not the same thing as validated evidence.

This pathway shows how RTH separates observations, a conceptual framework, manuscripts, prospective study development, and the future work required for independent validation.

  1. 01Observation & source recordsChronology, lived experience, clinical records, device data, and literature can generate questions. They do not automatically establish causation.
  2. 02Framework & synthesisThe Neurocardiac Model™ organizes a proposed pathway and makes assumptions and testable questions easier to inspect.
  3. 03Manuscripts & critiqueWhite papers, case analyses, and conference materials document reasoning and invite review. Prepared or submitted work is not the same as peer-reviewed publication.
  4. 04Prospective studyVariables, protocols, measurement strategy, ethics review, participant methods, and analysis plans translate the question into a study design.
  5. 05Independent validationReplication, external investigators, measurement validity, appropriate comparison groups, and transparent results are necessary before stronger general claims are justified.
Document statusWhere a document is in its lifecycle Evidence strengthWhat the underlying evidence can reasonably support Access levelWhat can be public, request-only, or controlled

Research publication pipeline

Scientific manuscripts and conference materials.

Status labels describe the current document state. They do not imply peer review, journal acceptance, conference acceptance, clinical validation, regulatory review, or institutional endorsement.

Submission-ready manuscript

Neurocardiac Model™ Scientific White Paper

A scientific synthesis of the evidence informing the Neurocardiac Model™, its five-stage observational framework, limitations, and testable research questions. The manuscript is part of the RTH research pipeline; no peer-review, journal-publication, or clinical-validation claim is made here.

Manuscript in preparation for peer-reviewed submission

Extreme Neurocardiac Coupling in a High-Functioning Survivor of Sudden Cardiac Arrest: A Seven-Year Longitudinal Case Analysis

A patient-authored longitudinal case analysis examining reproducible associations between cognitive-emotional activation and cardiac observations across an extended clinical record. The case is hypothesis-generating and does not establish causation.

Complete clinical communication document

Neurocardiac Clinical Summary Visual

A structured visual summary designed to organize chronology, measurements, observations, and questions for clinical review without substituting for the underlying medical record or independent physician interpretation.

Prepared for future conference submission

Neurocardiac Conference Abstract Package

Conference-specific abstract materials prepared for electrophysiology, cardiovascular, and resuscitation audiences. Submission, co-author, acceptance, presentation, DOI, and publication status must be verified separately before any such claim is displayed.

Preprint / submission transparency

An OSF DOI, journal name, submission date, review status, conference acceptance, or permanent citation will be displayed only after that specific milestone is independently verified. Placeholder DOI or submission language is not treated as publication evidence.

Study development

Prospective research infrastructure.

These documents translate the observational framework into testable research questions while preserving the distinction between planning, institutional review, data collection, and completed research.

Research planning document

Research Variable Matrix

Defines candidate variables, domains, measures, outcomes, covariates, and data-quality considerations for prospective investigation.

Access: Public summary / detailed materials controlled
Study-development document

Prospective Study Blueprint

Outlines a future prospective study architecture, including research questions, participant flow, measurement strategy, analytic considerations, and validation objectives.

Access: Available for qualified research collaboration
Protocol-development document

IRB Protocol

Research ethics and study-protocol materials prepared to support future institutional review. Listing this document does not mean an IRB has approved, sponsored, or opened a study.

Access: Full IRB materials available on request to qualified collaborators
Collaboration-ready document

Research Collaboration Proposal

A structured proposal for universities, health systems, investigators, and technical partners interested in methodological review, prospective validation, interoperability, or outcomes research.

Access: Available on request
Controlled evidence-support material

Device Telemetry & Source Documentation Index

An index of source documentation that may support qualified research or clinical review. Patient-specific telemetry, source records, and protected health information are not published as an open web download.

Access: Controlled review only

Clinician communication tools

Seven structured professional-facing resources.

These materials are designed to support clinical communication and pattern review. They are not validated screening instruments, diagnostic devices, clinical decision-support systems, or substitutes for the source medical record.

Professional communication tool

Physician One-Pager

Concise clinical communication summary designed to help a physician rapidly understand the framework, chronology, evidence boundaries, and questions for review.

Professional communication tool

Clinician Intake Packet

Structured intake material for organizing relevant history, symptom chronology, observations, and questions before a clinical or research conversation.

Professional communication tool

Symptom Summary Sheet

A compact patient-reported summary format intended to improve chronology and pattern communication without converting self-report into diagnosis.

Professional communication tool

Cardiorespiratory Summary Sheet

A structured communication aid for documenting patient-observed relationships among rhythm changes, breathing changes, symptoms, timing, and recovery.

Professional communication tool

Physician Outreach Packet

A professional introduction packet for requesting review, collaboration, feedback, or discussion of the research framework and supporting materials.

Professional communication tool

Why This Matters Clinically

A clinician-facing briefing that explains the practical research question, current evidence boundaries, and why structured longitudinal pattern communication may merit investigation.

Professional communication tool

Clinician Toolkit Bundle

A consolidated bundle of the clinician communication materials for qualified professional review and research collaboration.

Controlled distribution

Full IRB materials, patient-specific device telemetry, source medical records, protected health information, unpublished trade-secret methods, and other restricted evidence are not offered as unrestricted public downloads. Qualified researchers and clinicians may request appropriate review through the collaboration pathway below.

Evidence library entries

Research notes and evidence summaries.

Published RTH evidence entries identify source type, publication date, what the evidence supports, what it does not support, why it matters to RTH, and material limitations.

Source-reviewed evidence entries are being prepared.

The research pipeline above is public, while individual evidence-summary posts remain subject to source review and editorial preparation before publication.

Research integrity

Status is not evidence strength.

Document status

Draft, submission-ready, submitted, under review, accepted, preprint, and peer-reviewed are different states and must not be conflated.

Evidence strength

A case report or framework can generate hypotheses and organize observations but cannot establish population-level causation or clinical efficacy by itself.

Source protection

Public transparency does not require publication of protected medical records, raw telemetry, private identifiers, or trade-secret algorithms.

Research collaboration

Researchers, clinicians, universities, health systems, and technical partners may use this form to discuss methodological review, prospective validation, measurement, interoperability, or data-governance collaboration. Do not submit protected health information through this general inquiry form.

Research collaboration interest

Do not include medical records, personal health information, or information about a child. Privacy policy.